Thursday 3 January 2013

Brain imaging & scientific research into BPD

Okay, so in trying to learn more about BPD (Borderline Personality disorder) I cam eacross the following:



Reading more about this annotated brain image it transpires that a strong correlation was found for increased activity in an area slightly above the amygdala (increased amygdalar ventral striatal activity) and increased negative emotions in BPDs.

The connection between the frontal areas of the brain and the amygdala don’t work as it should in the brains of BPDs.

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 -SOOOOO...it IS all in my head, but not the way I think it is...it's not just imagined!!!
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The anterior cingulate cortex (ACC) plays a role in the regulation of emotion & putting the breaks on emotional responses.
BPDS have less grey-matter in the ACC.
A study showed that as the left ACC volume decreased parasuicidal behaviours increased and as left ACC volume increased impulsivity increased.

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-WOAH, just WOAH!!
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Elevated levels of glutamate, an excitatory neurotransmitter, was found in the ACCs of BPDs (when compared to the images of those without).
The higher the levels of glutamate the more impulsive the person is, no matter what diagnosis they have.
Higher glutamate concentrations were associated with dissociation as well as severity of symptoms in BPDs.

Reductions in the hippocampus,amygdala and ACC are not specific to BPD,they occur in other mental disorders such as PTSD and MDD (Major Depressive Disorder) and in people who have been exposed to trauma.

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-well...since i fall into more than one of those categories...
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~[http://commons.wikimedia.org/wiki/File:Borderline_Personality_Disorder_%28BPD%29_Abnormal_Brain_Structures.png]


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